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While the tests for interaction remained significant when the missing data were imputed (both as poor-intermediate and as extensive metabolizers), these tests were non-significant in the analysis excluding missing values, possibly due to the 18% reduction in sample size.
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The causes of damp-building syndrome are likely to be multifactorial and involve toxic, inflammatory, and allergic responses to microbes and their products; however, the underlying mechanisms, relative contributions of individual organisms, and potential for interactions remain poorly understood (IOM 2004).
For the rest to film comparison the trend for an interaction remained, F (2, 86) = 2.75, p = .07, whereas for the film to recovery comparison, F (2, 86) = 2.03, p = .14, and the rest to recovery comparison, F (2, 86) = 1.42, p = .25, the interaction was no longer significant.
When adjusted for established prognostic parameters, the interaction remained significant for RFS (p = 0.01) but not BCSS (p = 0.11).
The group by time interaction remained significant for the Inattention score of the DSM IV Rating Scale (FBB-HKS) and the Metacognition Index of the BRIEF after Bonferroni correction (Table 2).
The interaction remained significant after adjustment for family clustering (P=0.03).
The interaction remained significant after adjustment for maternal characteristics.
This interaction remained significant after adjusting for potential confounders.
The interaction remained significant after allowance for pathologic variables, and treatment.
Thus, this gene-diet interaction remained statistically significant even adjustment for waist circumference.
However, so far, the underlying mechanisms for their interaction remain unknown.
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