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The characterized binders also provide useful tools to study the role of GAK with traditional cell biology methods and can be used, for instance, in combination with a fluorescent tag to recognize endogenous GAK in cells.
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In the rehabilitation field, it can help in the effective design of better training and rehabilitation therapies, for instance, in combination with an FES system.
Semi-supervised learning is a combination of the two and uses a few labeled instances in combination with a large number of unlabeled instances to train a classifier and has shown promise in the area of review spam detection.
In these instances for the MS proteomics studies, evidence of phosphorylation by specific protein kinases typically includes a genetic requirement for the phosphorylation in vivo in combination with a match of the site to a well-defined consensus sequence.
For instance, limited stability of the NBT/BCIP under UV light in combination with a fluorescence mounting medium can complicate analysis and documentation.
CAU usually consists of pharmacotherapy in combination with a form of case management, for instance assertive community treatment [ 56].
In their experiment, used in combination with a legitimate justification for the request (for instance, that you have another job offer on the table), it seemed likely to backfire for participants.
However, no effect of the C6H was seen in the absence of an electron flow, for instance when used in combination with rotenone or malonate.
Yet sceptics may again underestimate how quickly both can grow and what Zynga, for instance, is worth in combination with Facebook: taken together they look much like Tencent.
For instance, mTORC inhibitors in combination with BCL-2/BCL-XL inhibitors showed dramatic pre-clinical efficacy in KRAS mutant colorectal cancers in vivo.
Several recent phase I dose-escalation clinical trials have also included [18F] FDG-PET, for instance in assessing MEK inhibition as a monotherapy or in combination with other drugs in patients with advanced solid tumors [10]-[12] [10]-[12]
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