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Again, the increased probability of locomotion in young male mice drives the increased number of observed locomotor bouts, ultimately accounting for increased locomotion in young male versus middle-aged male mice.
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Because of a lack of region selectivity and mosaicism of cre expression in fRIM1/KA-cre+ mice, it is difficult to pinpoint brain regions responsible for the increased locomotion to novelty.
Unilateral striatal infusions of the peptide by retrodialysis increased locomotion.
Disruption of dopaminergic neurotransmission also produced decreased courtship and increased locomotion.
For GIRK deficiency, the mice also displayed decreased anxiety, but in addition, these mice displayed increased locomotion [ 39].
Moreover, treatment with MTX results in an increased locomotion.
The fRIM1/KA-cre+ mice follow the same pattern except the increased locomotion is lesser in magnitude.
When plated on laminin myoblasts become polarized, elongated, and display increased locomotion 35.
Drd1 agonist treatment increased locomotion, an effect that was partially blocked by H-89 pre-administration.
Such treatments may also increase locomotion, producing an active cortical state that facilitates plasticity.
Additionally, a potential for increased stress on the aye-aye's long gracile digits is generated during its locomotion, especially while descending trees [ 27].
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