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Several prediction algorithms are available for in silico analyses.
The D. willistoni genome sequence was used for in silico analyses.
Sequences used for in silico analyses that detected the GBF/Gea-specific motif were identified by Blast using as queries the S. cerevisiae Gea1p (GenBank CAA89558.1)/Sec7p (NCBI NP_010454.3), Aspergillus nidulans GeaA (AN0112)/HypB (AN6709) or Homo sapiens GBF1 (GenBank AAI17683.1)/BIG1 (NCBI NP_006412.2).
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For sequence comparison of these two fragments see below the paragraph of "in silico analyses".
RV's novelty consists in starting the search for immunogenic antigens from in silico analyses of the pathogen's genome instead of culturing the microorganism [ 1].
Data resulting from in silico analyses were assessed for occurrence patterns in chosen taxa databases.
An in-house pipeline of in silico analyses was developed to search for EVEs in the A. vulgare genome sequences.
As alternative sigma factors, such as σB, are known to play critical roles in gene regulation across bacterial genera [ 33], we used L. monocytogenes 10403S and an isogenic Δ sigB null mutant as a model system for exploring the use of RNA-Seq, in combination with in silico analyses, for characterization of transcriptional blueprints associated with bacterial regulatory elements.
We prioritised the 338 genes for those likely to be important for ovarian cancer development by in silico analyses of copy number aberration and mutation using publically available datasets and identified genes with established roles in ovarian cancer as well as novel genes for which we have evidence for involvement in ovarian cancer.
In B. phenoliruptrix BR3459a, we found 26 proteins belonging to the T6SS, some of which appear to be membrane-associated proteins, while others are related to tailed bacteriophage components, but no function could be inferred via in silico analyses for the great majority of these proteins.
13 anti-inflammatory compounds were characterised and filtered out from medicinal plant species and analysed for RA by targeting TNF-α through in silico analyses.
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