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However, it is not possible to fully control for important confounding variables when using these administrative data.
Indeed, all these studies are subject to several limitations, including inadequate adjustment for important confounding variables, control group selection, extent of prior antibiotic exposure and measurements of resistance outcomes.
The multiple regression methods applied to additionally control for important confounding variables further limit the potential for systematic error in the estimated associations described in the present report.
In addition, most did not control for important confounding variables.
Finally, we used appropriate analytic methods to account for important confounding variables and the time-dependent nature of AEs [ 24].
Critical to the validity of this study is the success in matching cases and control patients for important confounding variables, especially the severity of underlying illness.
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A particular strength of the study is that we were able to control for a range of important confounding variables and to distinguish effects of antenatal, postnatal, and persistent exposure to maternal CMD.
The potential impact of important confounding variables was also neglected.
To investigate if patients with polycystic ovary syndrome (PCOS) who conceived via IVF treatment had a higher miscarriage rate than non-PCOS subjects after controlling for several important confounding variables relating to pregnancy loss.
In addition, we were able to adjust for several important confounding variables to explore the effects of BMI groups and CKD status in CVD events.
We were also able to adjust for several important confounding variables and to explore the effects of different weight change groups in separate genders.
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