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Due to the reduced patient-patient variation, these studies can be highly effective for identifying consistent gene-expression changes, such as the effects of (neoadjuvant) cancer treatment.
Statistical significance cut-offs are inherently arbitrary, and though they can provide a useful guide for identifying consistent patterns, they are directly tied to sample size and duration of follow-up [ 98].
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While extensive past efforts have been directed toward identifying consistent diagnostic markers for B. dorsalis s.s., B. papayae and B. philippinensis, this result is yet to be achieved.
Information for a given interval generally was available from only a single family, but data for 14 markers identified consistent differences along LG5.
An important role for Sp1 was identified, consistent with the regulation of ERβ target genes via association with the transcription factor ('tethered' mechanism).
Although there are no diagnostic tests for psoriatic arthritis, research has identified consistent features that help to distinguish the condition from other common rheumatic diseases.
To obtain a better insight into the genome-wide distribution of QTL and to identify consistent QTL for marker assisted breeding in cotton, an updated comparative QTL analysis is needed.
ChIP assays with the corresponding antibodies failed to identify consistent associations for Sp1, but upstream of the transcriptional start site there was binding of Sp3 and STAT3 (region 'f', Figures 3c and d).
An analysis of 6,324 orthologs among zebrafish, fugu, medaka, and spotted gar identified consistent evidence for genome-wide accelerated evolution in G. pachycheilus and only the terminal branch of G. pachycheilus had an elevated Ka/Ks ratio than the ancestral branch.
This also helps prepare for when payments are due, and identifies consistent 'late-payers'.
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