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Specifically, the IVV core data network shows a degree distribution that is approximately power-law degree, as well as a hierarchical organization and a tendency for highly connected (hub) proteins to interact with less highly connected proteins, as assessed by the degree distributions ([36]; Supporting Data VII in Text S1, Figure S8, and Table S9).
Using whole brain diffusion tractography and graph theoretical analysis, McColgan, Seunarine et al. identify a specific role for highly connected rich club regions as a substrate for structural connectivity loss in Huntington's disease.
To identify possible regulators within a given module, we looked for highly connected intramodular hub genes, i.e. genes that have strong connections within the module.
At the same time, we're continuously mapping the internet and building a system of record for highly connected internet data that analysts can search to uncover and block attackers targeting their organizations.
That might be atypical for the average Comcast broadband subscriber, but I think that type of usage is becoming a lot more common, particularly for highly connected people like me.
Moreover, the increase in packing density is observed for highly connected residues [34] and for solvent-exposed ones [30].
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As a practical matter, it is possible to use networks robustly storing k-cliques for detecting highly connected subgraphs with about k neighbors in large graphs.
Thus, we have decided to utilize various structural and physicochemical features of proteins, related to traditional QSAR properties for predicting highly connected proteins.
Fatigue cracking of rotor shafts is an important phenomenon that can lead to severe damage and great economic loss if not detected in time, especially for the highly connected and automatic production system in the Industry 4.0 factory.
For example, highly connected 'hub' genes are often highly expressed and evolutionarily conserved.
This was true for even highly connected 'hub-genes', which were still amenable to rewiring, indicating that the network may somehow buffer reconnective changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com