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For higher dose investigations, e.g. those above 10 mSv, Malone et al. suggest a more detailed informed consent procedure and forms specific for the examination [6].
Similar to the findings in the pelvis the risk for post-radiotherapy fracture is higher for higher dose treatment regimes and in females, particularly those over the age of 55 years.
Therefore, after oxide treatment, the CNTs, injected into mice of functional disorder, could inhibit content NO and increase the content Ach in stomach, and it was more favorable for higher dose of CNTs to reinforce the effect.
A third model for bystander effect, taking into account of spatial location, cell killing and repopulation, showed dose response curves increasing approximately linearly at low dose rates but quickly flattening out for higher dose rates, also predicting an effect augmentation following dose fractionation.
This effect size is similar to what was reported by Meduri and colleagues for a methyprednisolone infusion for early ARDS (0.54 point change in lung injury score over 7 days, P = 0.004) and smaller than that reported for higher dose methylprednisolone for late ARDS (1.3 point change, P = 0.001) [31],[32].
Thus, this trial reported responses similar to those described for higher dose, but with less toxicity.
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Women are more likely than men to be prescribed pain drugs, to use them chronically, and to get prescriptions for higher doses.
Drugs could be delivered right to a tumor, allowing for higher doses than possible now.
Supposedly proton machines will slash side effects and allow for higher doses that will cure more patients.
In the case of Ti6Al4V, peaks of the other allotropic form of TiO2, anatase, additionally appeared and became dominant for higher doses and temperatures.
We recognize that more thorough analyses, including inflammatory and immunogenicity endpoints, must be performed for higher doses of AH to conclude the protein's safety.
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