The entries of column E of Table 1 show that the RSCU' of most codons is either positively or negatively correlated with breadth of expression, indicating that indeed the high codon bias in the genes with low breadth of expression results from preference for different codons than in the genes with high breadth of expression.
Table 2 Wild Card assessment main (concise) results from the expert survey Wild Card Impact * = Low ** = Medium *** = High Breadth of effect Main Vulnerability Importance for decision makers Main weak signals Aviation Road Rail 1 1.
These patterns form "cascades" with different profiles: for instance, a fast-spreading rumor that's quickly snuffed out would have high breadth but little depth, and low virality.
For one immunogen, the neutralizing response was increased with a higher breadth compared to the Wild-Type.
Expression breadth, however, shows a contrasting pattern, i.e. longer genes have higher breadth of expression, possibly to ensure those structural features associated with gene plasticity.
Namely, there is a strong depletion not only of "high rate/low breadth", but "high rate/medium to medium-high breadth" categories of sites and proteins.
To understand the relationship between transmembrane transport and tissue expression breadth on protein evolutionary rate, we split all the genes into three equally spaced bins according to their tissue expression breadth (bin 1: lower breadth [range: 1 7, n = 2,828], bin 2: medium breadth [range: 8 14, n = 1,444], and bin 3: higher breadth [range: 15 22, n = 2,783]).
These costs can be attributed to a need for high product quality, material handling complexity, uncertain and fluctuating production volumes, and an unpredictable breadth of product variants.
This breadth of data collection coupled with contextual community-level data allows for high quality and innovative investigations prospectively exploring interactions between determinants at multiple levels.
But for higher fares the length and breadth of a nation, try Switzerland or Norway.
