Sentence examples for for hepatic damage from inspiring English sources
Understanding the cellular and molecular mechanisms that are responsible for hepatic damage and fibrogenesis is of key relevance in the field of fatty liver.
From these results it can be concluded that the exposure to 4-hydroxycyclophosphamide is predictive for hepatic damage after following courses.
Cell banks from different patient cohorts would be valuable in the weighting of genetic versus environmental factors that can synergize to produce the rare conditions required for hepatic damage by a drug at otherwise safe doses.
Elevated ALT has been used as a proxy for hepatocellular injury in previous studies (Clark et al. 2003; Ioannou et al. 2005; Lin et al. 2010; Ruhl and Everhart 2003) because it is more specific for hepatic damage than is AST.
Considering that increased MCP-1 forms also a vicious adipokine network causing insulin resistance and metabolic syndrome [ 34], both the chronic viral state itself and the host immune response can give rise to glucose and lipid metabolic disorders which, in turn, are risk factors for hepatic damage.
In this study, they found a strongly significant correlation between liver PFOS concentrations and serum alanine aminotransferase activity which they interpreted as indication for induction of hepatic damage.
TFEB gene transfer might provide an innovative therapeutic strategy for treatment of hepatic damage caused by AAT deficiency, which is a common cause of liver injury.
As a result, carbon tetrachloride (CCl4), which produces reactive free radicals when metabolized, has been widely used as a solvent for induction of hepatic damage in animal models [ 10].
Oxidative stress is a common pathogenetic mechanism that is responsible for the initiation and progression of hepatic damage after exposure to hepatitis C virus.
Evaluations were made for serum markers of hepatic damage, antioxidant enzyme, lipid per oxidation and liver fibrosis levels.
Available human studies do not provide an adequate basis for evaluation of hepatic effects, particularly given the limitations of serological measures of hepatic damage (Ott et al. 1983; Soden 1993).
