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These capsules have been developed as smart materials for guest molecule encapsulation and delivery in the last two decades.
In the polymeric architecture, SO2−4 serve as bridging coligands to connect highly puckered [Cu2 dps)2]n frameworks resulting in a 3D motif containing channels for guest molecule inclusion.
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On the other hand, the procrystal electron densities enable the visualization of sites available for guest molecules and therefore potentially usable channels in porous frameworks.
For example, they had been used as primary molecular templates or host for guest molecules in the subsequent multi-component self-assembly systems [4 8].
These materials with high functionalized shell wall could be good candidates for guest molecules adsorption, which is particularly useful in the biomolecules delivery for therapy and antimicrobial agent release for preventing caries.
In this case, such groups may act, e.g., as interaction site for guest molecules.
In addition, the internal cavity is occupied by two {Cu(CH3CN Br} groups, again disordered over four positions, which leaves no accessible volume for guest molecules.
The stability of the two kinds of MBB with the similar composition as unimolecular nanoparticles in water and their encapsulation capacity for guest-molecule were evaluated.
CDs form host guest inclusion complexes upon penetration of guest molecule in the central cavity of host CDs.
Chemical crystallographic analysis of the reported crystal sponge data allowed for unambiguous location of guest molecules for structural identification.
In particular, its higher water solubility (approximately 20 mM) [4, 14] and intermediate cavity volume (210 Å3) [15] make CB[7] (Figure 1) an attractive host for complexation of guest molecules used in biology and medicine [5, 6, 16].
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