Sentence examples for for greater potency from inspiring English sources

LLP derivatives (eLLPs) were engineered for greater potency against Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA).

As compounds are optimized for greater potency during pharmaceutical discovery, their aqueous solubility often decreases, making them less viable as orally-administered drugs.

Deadly in small doses, drug dealers and producers are using the opiate to either spike doses of heroin for greater potency at a cheaper cost or as a counterfeit for another drug like Norco, according to Sacramento County health officials.

Deadly in small doses, drug dealers and producers are using the opiate to either spike doses of heroin for greater potency at a cheaper cost or as a counterfeit for other drugs such as Norco, according to Sacramento County health officials.

This apparent ability of dasatinib to bind to ABL kinase in multiple conformational states indicates that it may have the potential for greater potency compared with imatinib.

Crystallographic studies of AMN107 indeed suggest that subtle differences in the mode of binding to Abl and a better topological fit to the Abl protein account for the greater potency of the drug (Weisberg et al, 2005).

15, 16 This review discusses the evidence for a greater potency of letrozole in aromatase inhibition, the apparent clinical correlates of this inhibition as gleaned from pivotal trials, and the design and undertaking of the Femara Anastrozole Clinical Evaluation (FACE) trial, specifically designed to resolve this issue unequivocally.

Although raltegravir has a higher CSF-to-plasma ratio of approximately 6% versus 0.5% for DTG, the greater potency of DTG results in a much higher CSF inhibitory quotient (ratio of drug concentration to IC50).

Additionally, in contrast to venlafaxine and duloxetine, which show greater preference for serotonin relative to norepinephrine reuptake inhibition, levomilnacipran has greater potency for inhibiting norepinephrine than serotonin reuptake.

While PPIs' have greater potency for acid suppression, their relative effectiveness for preventing clinically important gastrointestinal bleeding (CIGIB) is not established.

33, 34 In contrast, vemurafenib is a small molecule inhibitor of mutant BRAF developed through a crystallographic approach by Plexxikon Inc, resulting in greater potency for BRAF-V600E (IC50 31 nM/L, versus 100 nM/L for wild-type BRAF).