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Higher scale scores (ranging from 0 to 24) stand for greater functional impairment (cut-off ≥ 7; [ 14]).
Hence, the presence of the two distinct cell type-specific isoforms in vertebrates creates the potential for greater functional complexity than is seen in yeast.
Reasons for greater functional difficulties in some survivors are not entirely clear and cannot be entirely related to the degree of transplant complications, especially chronic graft-versus-host disease (GVHD) or prior therapy received by this population.
Kneeling and squatting are strong risk factors for knee OA, and this life style factor might account for greater functional disability as well as the prevalence of knee OA in Koreans [ 15- 17].
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Such duplication is consistent with the finding of extensive gene duplication for genes of great functional value in the blood feeding process, as suggested by Ribeiro et al. [ 77].
This is particularly important for meeting the greater functional demands of certain patients such as young people, athletes, military personnel, and professionals who exert high levels of physical effort [15].
However, in the between-group analysis for bilateral caudate nuclei, greater functional connectivity was observed for the autism group in the superior portion of area 6 in the left hemisphere and in the inferior portion of area 6 in the right hemisphere with Euclidean distances of 30 mm and 26 mm from the location of the FEF and respectively.
In a functional MRI study, Voon et al. (2010 b ) looked for and found a greater functional connectivity between the right amygdala and right supplementary motor area in patients with functional motor symptoms when they were exposed to stimuli of high emotional valence.
The objective of this study was to examine whether this sensitivity is due to a central pharmacokinetic (i.e., higher occupancy for a given plasma level) or pharmacodynamic (i.e., greater functional effects for a given occupancy) effect.
As navigation is an everyday behaviour of great functional significance for humans and most animal species, it is also possible that alternate mechanisms are at work that assure the encoding of these complex memories and their access on the long term even when consolidation was sub-optimal, as suggested by differential patterns of brain activity.
Moreover, several positively selected amino acids were located in specific regions known to be of great functional significance for the substrate specificity and enzymatic activity of type-A feruloyl esterases and lipases.
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