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With an increasing number of experimentally validated targets becoming available, utilising this additional information in the search for further targets may help to improve the specificity of computational methods for target site prediction.
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In the Asia-Pacific regional study, 22 sources were assigned proxy probabilities for some VEI relations indicating a need for further targeted data collection (all other sources were assigned probabilities based on known historical behaviour).
These results provide the basis for further targeted functional studies.
This information is valuable for further targeting of TB control.
Based on these insights, new strategies for further targeted-strain improvement may be designed.
The significant differentially expressed miRNAs identified by both SOAP and miRDeep2 approaches were selected for further target prediction analysis.
While the disruption of cre2 has increased secreted cellulase activity, further improvements could potentially be made using JKTR2-6 as a foundation for further targeted genetic manipulation.
Our data provide a rationale for further targeting of this novel stromal pathway in clinical trials, in conjunction with conventional chemotherapy.
GPR87 stands out as a candidate for further target validation due to its marked overexpression and correlation on a mutation-based level to squamous cell carcinoma.
The results generated by these assays offer for the first time the opportunity to examine co-infection patterns for selected enteropathogen species, and may form the basis for further, targeted enteropathogen testing and subsequent treatment decisions.
EGCG acts as potent and lipogenic-selective inhibitor of FASN, and do no exhibit adverse effects on body weight, therefore holding promise for further target-directed anti-cancer drug studies either alone or co-administered with other antitumoural drugs.
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