Sentence examples for for further replication from inspiring English sources

However, the challenge remains to prioritize SNPs from GWAS for further replication [ 1]; even if one would try to replicate only the top 1% with strongest genetic evidence 5,000-10,000 Sneedneed to be genotyped in replication studies.

The identified SNP loci may be considered as preliminary foundation for further replication studies and eventually unraveling the causal mutations for milk production traits in dairy cattle.

Two of these markers (rs10889553 and rs11195419) with consistent effects in KORA S3 and KORA S4 were selected for further replication in HYPEST (Estonian) cohort and in BRIGHT (UK) hypertensives-normotensives case-control sample set.

In Stage 2 a smaller subset of 19 SNPs were tested for further replication.

For further replication of a novel locus, analyses in two methods were performed, de novo and in silico replication analysis.

Following our analysis of the Stage 1 follow-up, we choose a smaller subset of SNPs for further replication in an independent data set.

Finally, even more important, a review of early programs shows that these projects did not take into account the factors for sustainability and further replication.

For this reason, further replication of the findings is needed in larger study populations with higher smoking prevalence.

However, although we found an enrichment of low P values and identified nine SNPs nominally associated with g (P < 0.05) that show interesting characteristics for follow-up, further replication will be necessary to meet rigorous standards of association.

To test for such stable and distinct states we continued the simulation for 20 generation times, without further replication, and examined the Lys/Lyt ratios (see Methods).

The analyses of these additional families, combined with the original 2,319 families [ 2], provided protection from population stratification bias, and increased power to provide further replication support for the associations of these 18 susceptibility loci [ 2].