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The Sporothrix system may bring new opportunities for functional studies in order to understand the biology of fungi and infection.
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This illustrates the relevance of functional studies in order to assign phenotype-associated SNPs to causal genes.
Upon further inspection of the overlapping genes of these two clusters, the extracellular wnt signaling antagonist Wif1 was selected as a candidate for functional intervention studies in order to define its role during cardiomyocyte differentiation.
De Rybel, B. et al. A versatile set of ligation-independent cloning vectors for functional studies in plants.
Furthermore, functional studies are required in order to explore the underlying mechanisms.
Despite the manually curated evidences shown here, we believe functional studies are necessary in order to confirm this assumption.
The COGs database provides 17 functional categories for orthologous groups in order to facilitate functional studies and serves as a platform for functional annotation of newly sequenced genomes and studies on genome evolution [ 4].
Mitoxantrone and daunorubicin accumulation studies were also performed on the glioblastoma cell lines used in our study, in order to test for the presence of functional P-gp and/or BCRP efflux pumps on these cell lines.
This study suggests a rapid redistribution of functional weights in order to compensate for interference.
These data highlight the need for a range of functional studies to be performed in order to identify variants with partially compromised function.
It's functional in order to keep our relationship alive.
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