Sentence examples for for functional screening from inspiring English sources

Several heterologous expression systems have been used for functional screening of just confirmation of P450 activities, including Escherichia coli, yeasts, insect or mammalian cell cultures, and plants.

The inability to identify some cellulases in function-based screening was anticipated and may be explained by a potential lack of expression of the enzymes from their native promoters in the E. coli expression host, an inability to be translated due to differing codon usage, or an inability to be secreted and/or active under the conditions used for functional screening.

Based on the annotation information, we generated genome-wide human and mouse cDNA and shDNA E3 collections ready for functional screening.

The limited knowledge of the function of members of the large E3 superfamily prompted us to generate genome-wide E3 cDNA and RNAi expression libraries designed for functional screening.

These nine SNPs were selected for functional screening (Table 1).

Genetic sensoring represents a new approach for functional screening of synthetic derivatives of vitamin D3.

We also discuss new frontiers in pooled screens, including novel effector domains for functional screens and applications in the noncoding genome.

This opens up the unique possibility to generate patient and CFTR mutation-specific cell lineages, carrying halide- or voltage-sensitive fluorescent proteins for functional screens or reporter tags within the endogenous CFTR gene for direct visualization of trafficking.

The MEA recording method utilized here is non-invasive, thus long term chronic measurements are possible and it does not require precise positioning of electrodes, thus it is ideal for functional screens.

With this in mind, we hit-picked cDNA and plasmid-encoded RNAi (shDNA) expression constructs representing nearly the entire human and mouse E3 families from publicly available genome-wide collections, and individually arrayed these constructs in 384-well plates for functional screens [17].

Cells at passage 4, with or without 10 ng/ml EGF were plated for functional screens and dose response studies.