Sentence examples for for functional integrity of from inspiring English sources

Their dynamics is considered to be essential for functional integrity of the organelles and thus for the cell viability.

In fact, up-regulation of p21CIP/WAF-1 may serve as a read-out for functional integrity of the p53 gene in malignant cells [ 2, 24- 26].

After the development of the structural components, additional proteins such as Usherin seem to be required for functional integrity of the photoreceptors.

This reduction was mainly through the loss of genes needed for living freely, or through migration to the nucleus of genes required for functional integrity of the mitochondrion [ 5].

Functional differences between the cells in an organism are defined by epigenetic factors and epigenetic programs, which are critical for the preservation of functional integrity of the cellular phenotypes [ 1- 3].

Treatment with HaE prior to or after DMBA intoxication for 7 days caused a marked decrease in the levels of serum AST, ALT, and GGT activities; however this decrease was significant following treatment with HaE prior to or after DMBA administration at the tested dose for 14 days indicating maintenance of functional integrity of hepatic cell membrane.

As an important cargo binding subunit of dynein (Ha et al., 2008), dynein intermediate chains (DYNC1I1 and DYNC1I2) are necessary for the functional integrity of dynein (Figs. 5 and S4) and the maintenance of neuronal architecture (Fig. 1).

Taken together, our results suggest that SMN is required for the functional integrity of the U body P body pathway, which in turn is important for maintaining proper nuclear architecture.

A recent study by Mayer et al. [20] demonstrated that 150 300 nt-long RNA transcribed from the rDNA promoter region is required for the functional integrity of the NoRC complex, which is involved in heterochromatization and silencing of rRNA genes.

Since CD4+ T cells constitute the major IL-2 producing population that is important for maintaining functional integrity of other immune effectors including CD8+ T cells, a loss of IL-2 producing capacity of CD4+ T cells could produce a domino effect eventually for the overall immune deficiency.

VE-cadherin is crucial for the functional integrity of endothelial layer [ 70] and contributes to all phases of AG.