Sentence examples for for functional implications from inspiring English sources
However, evidence for functional implications of MITEs in gene regulation through small RNA pathways is still lacking.
Since the global analysis does not reveal a direction in the changes and lacks functional detail, we scrutinized the pathways with most pronounced regulation for functional implications.
These files provide a rich data set that can be mined in many different ways for functional implications (see the discussion below).
We performed bioinformatics and cis-expression quantitative trait loci (eQTL) analysis for functional implication of the identified SNP.
There is a variety of methods for the prediction of functional implications of missense mutations, each of which utilizes a different heuristic (see recent reviews [ 18, 19] as well as examples of recent methods [ 20- 22]).
Given the key role of CD8+ T cells in viral clearance, our work provides valuable insight for the functional implications of HBc141 149 epitope-specific T cell response in HBV infection.
Studies on leukaemias have provided paradigmatic examples for the functional implications of genetic and epigenetic alterations in cancer development [ 25, 26].
Additionally, the list of genes with high Ka/Ks values by intra-species comparisons can be further explored for potential functional implications.
This variant is one of few for which the functional implications are known: 66Met-BDNF localizes poorly to intracellular granula compared to 66Val-BDNF.
The differential localization and dynamics of TβRI and TβRII in adhesion-rich domains, relative to one another and to the whole cell TGFβ receptor population, indicates that this spatial control has functional implications for TGFβ signaling and for mechanotransduction. 10.7554/eLife.09300.010 Figure 4. Dynamic interaction of TβRs with integrins facilitate spatial organization.
The conformational flexibility of the N-HEAT region may provide significant functional implications, for example, adopting different conformations for the interactions with various mTOR regulators (Kim et al., 2008; Wullschleger et al., 2006; Zoncu et al., 2011).
