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Changes in the composition of basement membranes are likely to be responsible for functional disturbances and hence for the development of capillary disease.
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This may cause disturbances in androgen-dependent processes including Cx43 (de regulation, however, we can not exclude the possibility that in response to flutamide decreased Cx43 expression may represent one mechanism responsible for functional disturbance of the boar epididymis.
A decrease in AR protein levels results in altered androgen signaling which may cause disturbances in androgen-dependent processes including Cx43 (de regulation, however, we can not exclude the possibility that in response to flutamide decreased Cx43 expression may represent one mechanism responsible for functional disturbance of the boar epididymis.
Identification of several hits in such a functional assay provides a good starting point for future characterization of the compounds by more phenotypic assays and for correlations of functional disturbances with, e.g., transcriptome changes.
The 8 clusters of functional disturbances having enrichment scores over 2 are presented in Table 2.
Otalgia is also a very common symptom of functional disturbances of the masticatory system [ 5].
In light of the findings presented here, healthcare professionals responsible for the medical evaluation and management of individuals with concussion should recognize the potential for missed functional disturbances resulting from the concussion if the patient report of symptoms is over-relied upon.
It is common for an individual with stable ECU tendinopathy to describe a growing awareness of functional disturbance and pain.
However, clinical trials based on this measure may lack sensitivity for the detection of early functional disturbances.
Such functional disturbances may underlie a tendency for enhanced altruism driven by empathy-based guilt observed in some patients.
However, our results were obtained for healthy asymptomatic knees with undetectable either structural or functional disturbances.
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