Sentence examples for for functional conservation of from inspiring English sources
When tested for functional conservation of Rif1 function in dRif1, we find that it does not perturb or complement yeast Rif1 and does not relocalize to DNA damage foci in HeLa cells.
This case excludes restricted taxonomic functionality and provides additional evidence for functional conservation of syntenic orthologs as defined by "gatekeepers" on a broad phylogenomics range.
To test for functional conservation of GATA3 between zebrafish and human, we examined HDR tissue homologs in our zebrafish mutant.
Together, these data provide a strong argument for functional conservation of the role of the PAG in vocalisation.
It is common practice to use complementation analysis to verify knockout phenotypes in P. patens, and cross-species complementation has been used to test for functional conservation of vascular plant and P. patens proteins (e.g., Bravo-Garcia et al., 2009).
Thus, our data provide support for functional conservation of TBPH /TDP-43 and are consistent with the hypothesis that TDP-43 evolved early in animal evolution to play a fundamental role in the differentiation and cellular function of complex nervous systems.
Overall, our findings indicate a significant role for the functional conservation of chromatin organization in the molecular evolution of eukaryotic genomes.
At the protein level, the effect of purifying selection was largely predominant and this accounted for the functional conservation of the three drug targets.
This measure used only the human ChIP-seq data and provides a maximum threshold for the functional conservation of each human regulatory region, based on the alignability of its DNA to the genomes of the other 19 species.
However, this lack of sequence similarity did not result in a lack of conservation by position, which could indicate a conservation of function as it has been shown earlier that positional conservation also accounts for functional conservation [ 15, 30].
However, we regarded the sequence homology based annotation of proteins as strong evidence for functional conservation.
