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The average extraction yield of the C1000 and CSIII traps was quite low, except for few compounds like ethyl acetate and propanol.
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In other words, rather than producing detailed, gender, ethnic or age-specific ranges for hundreds or thousands of patients for a few compounds, we instead produced a broad survey for hundreds or thousands of compounds from a relatively modest number of individuals.
For most analytes, two MS/MS transitions were acquired, although for a few compounds it was difficult to obtain characteristic abundant fragments.
For a few compounds (i.e. anabasine, theanine, caproic acid, fumaric acid and protopanaxatriol), up to a 10-fold increase in sensitivity was noticed with UniSpray.
Field measurements of ambient concentrations and above canopy fluxes have validated emission estimates for a few compounds from some important landscapes.
However, for a few compounds mass measurement errors as high as 16 ppm were observed in individual measurements.
Except for a few compounds unique to the H2O (extract 5) and EtOAc (extract 3) extracts, the majority of compounds were successfully extracted with EtOH (extract 4).
Laboratory methods are also under development for pesticides in saliva, meconium, and amniotic fluid, although validated methods are available for only a few compounds.
Here, too, despite the institution of a standardized protocol for developmental neurotoxicity, few compounds have actually been tested relative to the total number of concern, even after mandated call-ins for data by the U.S. EPA (Makris 2006; U.S. EPA 2006).
As the development of new drugs for the treatment of TB has been neglected for decades, only a few compounds have currently reached the clinical stage of evaluation.
Besides, Figure 1 shows the distribution of the number of known ligands per target for each dataset and illustrates the fact that for most of them, few compounds are known.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com