Sentence examples for for extensive optimization from inspiring English sources

Above results illustrate that 2d is an interesting lead for extensive optimization to explore new drug candidate for AD therapy.

mESCs were used as our initial model, allowing for extensive optimization of seeding and culture conditions.

Thus, we expect this approach to be effective for improving the yield of a variety of recombinant proteins without the need for extensive optimization.

Other steps of gene regulation can be investigated by polysome extraction and RNA sequencing to determine the pool of RNAs that are under translation (associated with polysomes), but this has proved difficult to transfer between species, due to the need for extensive optimization [ 40].

The physical components, a library of capture antibodies, and the secondary reagents of the Q-Plex™ system have undergone extensive optimization for consistent implementation [ 18, 19].

An alternative approach for quantification of the PS's intracellular localization could involve organelle-specific fractionation, for example, by centrifugation techniques and analysis of the organelle-bound PS fluorescence this approach is more time-consuming and may require more extensive optimization for the particular cell type.

Their clinical utility, however, has been limited chiefly due to their slow clearance from the circulation, longer retention in non-targeted tissues and the extensive optimization required for each antibody-tracer.

For both primer based chemistries, extensive optimization of primer concentrations was required to minimize the formation of primer dimers.

Unlike the CPN delivery method, the optimal conditions for delivery of siRNAs by electroporation require extensive optimization [ 34] of the voltage and pulse time to ensure high transfection rates.

In recognition of the expectation that 100% accuracy is a requirement, even under suboptimal conditions, the assays developed for the targets in this report have undergone extensive optimization to maximize accuracy even under less than optimal conditions.

Aggarwal et al. and George et al. have shown in their studies that high titers for B strains can be achieved after extensive optimization of moi, microcarrier concentration, agitation rate and CCI [ 10, 47].