The envisioned products are examples of executable biology [ 6- 8], which are useful for systematically exploring hypotheses about referent mechanisms through virtual experimentation.
As a pilot project designed to explore hypotheses for a larger placebo-controlled trial, no adjustments for multiple comparisons were included [34].
To explore hypotheses for changes in incidence related to age, we analyzed electronic laboratory data for Campylobacter infections reported in England and Wales from 1990 through 2007.
To explore hypotheses for age-related changes in the incidence of Campylobacter infections in England and Wales during 1990 2007, we analyzed electronic laboratory data.
We adapted a previously developed mathematical model for the transmission dynamics of typhoid in South Asia [ 16] by fitting to the data from QECH and modifying the model to explore hypotheses for the increase in typhoid fever cases beginning in 2010.
To explore hypotheses for the increased number of typhoid fever cases in Blantyre, we fit a mathematical model to culture-confirmed cases of Salmonella enterica infections at Queen Elizabeth Central Hospital, Blantyre.
We identify potentially differentially expressed transcripts related to polyphenism and use differential expression to explore hypotheses for the involvement of two important biological processes, immunity and olfaction, in the life cycle of the bee.
Whereas inductive models are useful for positing explanations of patterns observed in large amounts of data and when precise prediction is required, abductive models are useful for exploring mechanistic hypotheses and when uncertainty is pervasive [ 21],[ 27].
Despite recent advances in genetics and imaging, the neurobiology of ASD remains largely obscure indicating that there is ample space for exploring new hypotheses regarding the etiological basis of the disorder [44].
