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This would apply equally to new agents and to new adult height indications for existing agents.
The identification of new therapeutic uses for existing agents has been proposed as a means to mitigate the escalating cost of drug development.
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The lack of new antibiotic classes calls for a cautious use of existing agents.
Emphasis is placed on the advanced development of existing agents since 2011 and new agents identified as radiation countermeasure for ARS during this period.
Such a recommended approach should "shift the burden of proving safety to manufacturers prior to new chemical approval, in mandatory post-market studies for new and existing agents, and in renewal applications for chemical approval".
In conclusion, RA has single-agent activity in relapsed, sensitive SCLC with manageable toxicities but is unlikely to provide any superiority compared to existing agents for this disease.
Therefore, there is a clear need for development of new and more effective therapies for controlling advanced atherosclerosis, and existing agents, or novel compounds that target known key factors, may eventually be shown to have efficacy for treating and stabilizing advanced atherosclerosis.
(Kennedy taught himself screenwriting after adapting his novel Legs for the screen, fired his existing agents and hired the kind of movie agent at William Morris who "got me more money at a 15-minute luncheon to write a treatment than I'd made all year as a teacher").
The role for the center remains to be clarified but should include monitoring for novel infections and research into existing agents.
Existing agents exert their primary actions on monoaminergic systems.
This site is dedicated to both existing agents and hopeful agent candidates.
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CEO of Professional Science Editing for Scientists @ prosciediting.com