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Jeffery and coworkers [3] compared gene sets generated by 10 different feature selection methods, for example, significance of microarrays (SAM), analysis of variance (ANOVA), empirical Bayes t-statistics, and found that there was a big discrepancy in gene sets produced by different algorithms.
For example, Significance Analysis of Microarrays (SAM) (Tusher et al., 2001) and Gene Set Enrichment Analysis (GSEA) (Subramanian et al., 2005), which detect differentially expressed genes and gene sets, respectively, are two well-known techniques that use permutation tests to compute statistical significance.
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For example, the significance of 2-fold change from 2 to 1 peptide spectral counts is not equal to the significance of 2-fold change from 20000 to 10000.
So how are scientists to evaluate, for example, the significance of the handful of fossilized examples of osteosarcoma, a rare bone cancer that mostly affects young people?
For example, the significance level for dividend yield decreases from 5to2.17%7%.
For example, repeated significance tests boundaries, and other boundaries, are being used in clinical trials more and more often.
The relationship between design and NPD outcomes is also strongly moderated by contextual factors; for example, its significance is only evident for organisations, which also engage in in-house R&D.
They include, for example, the significance of the migrant's gender and the martial status variables in the corrected OLS models as well as the insignificance of these variables in the corresponding Tobit models.
The current body of information on the healthcare sector, which while comprehensive, fails to answer some important questions; for example the significance of growth and employment in the oral healthcare sector, which unlike the healthcare sector as a whole cannot be incorporated as such in NA categories.
For example, the significance level α = 1% for fosmids is realized for roughly all δ ≥ 8 kb at ρ = 8× physical coverage.
The cases had more common co-morbidities, but compared to infections for example the significance of cardiovascular disease was much less, 13% of the visits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com