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The most sophisticated coupled ocean-atmosphere climate models still often differ from observations, for example persistently exhibiting a double ITCZ or failing to produce the proper magnitude and periodicity of modern ENSO variability.
For example, persistently activated STAT3 is found in 50% of lung adenocarcinomas and is primarily observed in tumors harboring mutations in the epidermal growth factor receptor (EGFR) [37], [38].
For example, persistently elevated GDF-15 levels may be more strongly correlated with poor outcomes.
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For example, it persistently and effectively pushed the flat tax idea, which should be-come effective Jan . 1 , 2004
For example, host cells persistently infected with defective HIV virions can become highly pathogenic upon coinfection with a competent virus (Iwabu et al. 2006).
For example, people who are persistently sad, hopeless and suicidal, and who have trouble eating and sleeping, generally respond well to various antidepressants and different types of psychotherapy.
Conversely, if the pivotal point of IL2 gene regulation by FOXP3 is circumvented, for example by autonomous signaling via persistently active JAK3/STAT5, then malignancy could result, as shown experimentally by over expression of STAT5 [64].
The people of Linxian County in China, for example, are known for their persistently low intake of several micronutrients and high risk of esophageal cancer (Blot et al. 1993).
For example, becoming impaired or being persistently impaired on functional status predicted all three selected psychosocial problems, including depression.
For example, a constitutively active Ras persistently induces the phosphorylation of Smad3 at its linker region [ Figure 2B (24, 24), supplementary Figure S2 is available at Carcinogenesis Online].
For example, while proviral DNA is detected persistently over decades in some SFV infected humans; other individuals develop antibodies to SFV without detectable proviral DNA.
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