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There have been literatures which have focused limited topics of control engineering, for example manipulating transfer function, considering stability etc.
For example, manipulating the relative sound levels in a multilevel structure makes it possible to vary perceived event rate while keeping the overall density of perceived events constant, which may be particularly useful for keeping activity related to sensory processing constant in brain imaging experiments.
For example, manipulating the shape and size of cell clusters allows the control of differentiation of embryonic stem cells [9], of the branching of mouse mammary epithelial tubules [10] and induces the polarisation of primary rat astrocytes [11].
For example, manipulating the mode of self-focus influences autobiographical memory specificity, problem-solving ability, and emotional recovery from a laboratory-induced negative event, where relative to analytical self-focus, experiential self-focus has more adaptive effects (Sanders & Lam, 2010; Watkins, 2004; Watkins & Moulds, 2005; Watkins & Teasdale, 2004).
Therefore, for example, manipulating the time required to maintain the representation of the standard stimulus in the sensory memory (interval between the consecutive stimuli) may tell if the ERPs to facial expressions are subordinate to the sensory memory, as the MMN has found to be (for the auditory MMN, see e.g. [ 47]; for the visual MMN, see [ 8]).
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Mendel, for example, manipulated pea plants, but he was interested in learning about the phenomenon of heritability generally.
Gilchrist [11], for example, manipulated an occlusion cue to alter the apparent depth of surfaces.
For example, by manipulating the structure and distribution of nanoparticles the researcher can impact macroscopic properties of the nanofluid, such as its thermal conductivity.
For example, by manipulating the degree of semantic correspondence between odour-picture pairs, Gottfried and Dolan [37] revealed facilitation for semantically congruent versus incongruent situation.
For example, when manipulating a given object, decay would prevent the application of unnecessarily high grip force [ 31].
For example, when manipulating a particular object, it may be beneficial to optimize the motor memories associated with other similar objects (objects with similar mass or frictional properties).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com