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We also expanded to two-tailed analyses to enable tests for dispersion of functional annotations since, for example, localization near the nuclear periphery is functionally relevant [ 13].
For example, localization of ASH1 mRNA in yeast requires the function of Loc1p, an RBP that is exclusively nuclear (Long et al. 2001).
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For example, a localization service can be added when an application is run that requires location information.
For example, mitochondrial localization sequences and N-terminal transmembrane anchors are frequently interpreted as signal peptides [ 44].
For example, nuclear localization of galectin-7 was associated with the initiation of tumorigenesis in laryngeal squamous cell carcinomas [ 27].
Tissue heterogeneity due, for example, to localization of stem and progenitor cell populations can result in sampling variation [ 21- 24].
For example, asymmetric localization to the P-D sides of cells will give higher mean intensities on cell edges in the A-P orientation.
For example, HEX localization is nuclear in endodermal cells that give rise to the liver, while it is cytoplasmic in cells lateral to the liver-forming region [ 7].
For example, nuclear localization signals (NLS), nuclear export signals, (NES) and other nuclear related domains were over-represented in stable proteins and under-represented in unstable proteins.
In Drosophila, for example, the localization of mitochondria around the fusome, the cytoplasmic structure that allows material transport to the oocyte, is dependent on microtubules [ 4].
For example, heightened localization of synaptic proteins in one region indicates specificity of synapses varies with brain region and presumably function within that region (15).
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