Exact(4)
Excess alcohol cannot always be used, for example, in the synthesis of triacylglycerols using a protected glycerol.
A more reactive fatty acid derivative such as the acid chloride or anhydride is used, or the fatty acid reacts directly with the alcohol, using dicyclohexylcarbodiimide and 4-dimethylaminopyridine as a coupling agent, for example, in the synthesis of acylglycerols.
Some enzymes are used commercially, for example, in the synthesis of antibiotics.
A strength of this study is the use of human cells, which is not trivial as significant differences exist between humans and mice - even for example in the synthesis of P-selectin, which can occur via NF-κB in rodents but requires completely different cytokines (for example, IL-4) in humans [ 3].
Similar(56)
Methotrexate, for example, disrupts the synthesis of DNA and ribonucleic acid (RNA).
For example, the synthesis of α-ketoglutarate through transamination reactions could be used in the TCA cycle to provide energy.
For example, TRIM25 is involved in the synthesis of IFN-β through the RIG-I pathway [ 30].
For example, biocatalytic transformations are used in the synthesis of optically active alcohols.
For example, in protein synthesis mRNAs are localised to vertices of the cytoskeleton, if tension imposed by the integrins is prevented, protein synthesis is inhibited.
For example, in rats the rate of muscle protein synthesis is approximately 2.5-fold greater than that of humans.
For example, ACACA catalyzes the rate-limiting reaction in the synthesis of long-chain fatty acids [ 42].
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