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In summary, it is clear that inhaled NO has distal effects outside the lungs that may be harnessed therapeutically in the future; for example, in the prevention of ischemia-reperfusion injury.
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Studies have reported that anti-inflammatory molecules such as IL-10 [ 18, 19] show efficacy in animal-model gene therapy for example, in the prevention of autoimmune disease, such as rheumatoid arthritis, multiple sclerosis, and autoimmune thyroiditis.
"No one is, for example, proposing the prevention of violence," says Vega. "Everyone is talking about repression and the stronger the better, because that fits with people's conviction that the solution lies in the use of force".
For example, in the case of statins, the evidence supporting their prescription for primary CVD prevention is highly controversial.
For example, the prevention of facial mimicry impairs the detection of a change in emotional facial expressions [16].
For example, in the placebo-controlled Fracture Prevention Trial, the reduction in risk of non-vertebral fractures was not seen until 9 12 months after starting teriparatide (7).
For example, in the diabetic foot accurate identification is essential to define the treatment for prevention of (re)ulceration.
Moreover, the architecture of the studied ICUs might play a beneficial role in the prevention of delirium (for example, the presence of visible daylight and a clock).
Another example would be the prevention of necrotic enteritis in broiler chickens.
Because the safety of this system in clinical settings has already been demonstrated, the system can be used for the evaluation of footwear for prevention and therapy, for example, the study of footwear for the prevention of callus formation in diabetic patients and the evaluation of the risk of fall during gait in the case of elderly using their own shoes.
For example, the zoledronic acid study of fracture prevention in hip fracture patients showed greater ability to prevent further (clinical) spine fractures and a more modest and non-significant benefit in the prevention of further hip fractures [ 19].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com