PCA is a standard tool in population genetics, and has been used, for example in a study of 23 European populations [1] and more recently of 25 Indian populations [2].
For example, in a study among the Dutch population, effect estimates were different for European descendents and non-European immigrants [ 27].
For example, in a study by Kramer et al. [ 30], various alcohol-based hand-rub gels accepted by ASTM standards failed to pass the European standards.
For example, in an earlier study of TCF7L2, the strongest risk variant associated with type 2 diabetes in multiple European populations was found in the T allele of rs7903146 at the 5′ end of the gene [ 9].
For example, in a genome-wide pharmacogenomic study using 516 LCLs derived from a cohort of European descent, an eQTL (rs477692) in MGMT was identified to be associated with cytotoxic response to temozolomide (24).
For example in a meta-analysis of 8 European studies, Veldt et al. reported regression of fibrosis in approximately one third of patients achieving SVR [ 106].
For example, the latest European Study of Cohorts for Air Pollution Effects (ESCAPE), including 312,944 subjects from 17 European cohort studies, showed a 22% increased risk of lung cancer associated with every 10 µg/m increase of PM10 [3].
For example, in one European Journal of Applied Physiology study, when young men spent 10 minutes cycling, three times over the course of 3-plus hours, they reaped greater cardiovascular benefits than those who knocked out all 30 minutes at once.
Now, in theory this isn't such a problem: renting is the norm, for example, in many European nations.
For example, in some European countries, governments pay for the insurance of nuclear power plants.
