Sentence examples for for example by activating from inspiring English sources
Omega-3 supplementation, DHA in particular, has also been shown to modulate gene expression at the transcription level, for example, by activating peroxisome proliferator-activated receptor (PPAR) family members [ 85] and the mRNA stability of several enzymes associated with glucose and lipid metabolism [ 86].
Agents designed to activate the cell death machinery directly, for example by activating the death receptors expressed by melanoma cells, could break drug resistance, and they may achieve long-lasting therapeutic success.
Thus, strategies aimed at shortening the treatment phase, for example by activating quiescent cells, will not reduce the chances that treatment fails as a result of drug resistance.
The content of this intervention can take several forms, for example, by activating positive stereotypes or highlighting important values in these individuals (ie, the self-affirmation technique).
As a consequence they are targeted into the secretory pathway and once extra-cellular play a –autocrine, paracrine, or endocrine- signaling role for example by activating G-protein coupled receptors of neighboring or more distant cells.
Efforts to increase fatty acid oxidation, for example by activating AMPK, have been only partially successful because of a lack of concomitant alteration in the energy status of a cell [ 22, 47].
For example, mTOR by activating S6 kinase causes insulin resistance.
For example, by stimulating the activating PPI between MOB1 and LATS1/2[9], an efficient decrease of YAP/TAZ activities might be obtained.
NO plays an important role in cartilage destruction in OA - for example, by inhibiting matrix synthesis, activating MMPs, and inducing chondrocyte apoptosis [ 33- 35].
In contrast, non-canonical Wnt signaling activated for example by Wnt5a and Wnt11, inhibits the transcriptional activation of β-catenin but also triggers calcium signaling and JNK activation [4], [5].
Trypsin may affect various cellular functions, for example, proliferation and invasion, by activating protease-activated receptors (PARs) and especially PAR-2 (Soreide, 2008).
