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For example, a PDS with 10 proteins (A1, …, A10) and patient i has a high ratio value on Ai and low ratio value on the other 9 proteins; this PDS will get a higher score than a PDS of size 4 with all patients having medium ratio values on all 4 proteins in this PDS.
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For example, a-pple.
For example, a translational PK-PD model was developed to describe the time-course of the drug-induced thrombocytopenia by separating system-specific (platelet baseline level, maturation time, rate of progenitor production, feedback regulation) and drug-specific (e.g., drug potency) parameters.
For example, a pharmacokinetic (PK /pharmacodynamic (PD) model predicting inhibition of interleukin-6 and tumor necrosis factor-α after high intravenous doses of erythromycin predicts little or no inhibition of interleukin-6 and tumor necrosis factor-α at 250 mg once daily, a dose that produces reductions in exacerbations of bronchiectasis.
For example, an in vitro PD model is much needed for large-scale drug testing.
For example, all PD patients who received a TRODAT within one year since the onset of symptoms were grouped into one group.
This is not possible in real terms, as for example a patient cannot first die during PD then later have a renal transplantation.
The connections between disease nodes were identified by the use of protein interactions, for example, a strong connection between FTD and PD detected by their large cluster of protein interactions.
For example, PD-1-PD-L1 pathway has been shown to impair Th1 immune response in the late stage of infection with Mycobacterium bovis bacillus Calmette-Guérin, thereby facilitating the bacterial persistence in the host [ 28].
For example, a recent article in the medical journal of Neurology suggests that those with Parkinson's disease (PD) need to be extra careful about overall sun exposure (3).
For example, a parrot.
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