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Structurally, the α, β-unsaturated ketone moiety was introduced into the tropinone scaffold, which should be responsible for enhanced activities.
Increased levels of regulatory proteins and co-factors of different fungal mutants are considered responsible for enhanced activities of β-Xylosidases.
Computational approaches such as cheminformatics and virtual screening, pharmacophore development, molecular docking and molecular dynamics are mainly used to identify new agents, define molecular determinants for enhanced activities, design and evaluate more efficient drugs with improved safety [42].
Medical Education/Pre-Service Education/Pre-Service Education thEncouragevailable WHO matheials for medical, nuseing, and pharmacist/drug seller pre-service educatiof as the basis for enewlyed availables in this area, to provide a foundation of appropriate practitioner behaviour for the future.
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Circumstantial evidence indicates that ureide-transporting plant species, such as pecan, possess a higher Ni requirement than amide-transporting species [ 23]; thus, raising the possibility that ureide transporting species might possess enzymes, other than the standard ubiquitous urease, that require Ni for activation or for enhanced activity.
The results provide a chemical rationale for enhanced activity in certain cyclic antimicrobial peptides and can be used as a guideline for design of novel antimicrobial peptides.
The design of such system is beneficial for enhanced activity from morphology control and composition adjustment, which would provide some new pathways for the design of promising photocatalytic systems for enhanced performance.
The present results confirm predictions of computational modeling that an aryl substituent can be introduced at the 2-position in structure 3. The substituent is anticipated to project deeper into the binding site and provide opportunities for enhanced activity and selectivity.
The planet appears to be responsible for enhanced activity in the chromosphere of its star.
This lead compound may be useful for manipulating components of retinoid signaling networks, and may be further derivatized for enhanced activity.
Huang et al. (2014) showed that oncogenic Kras requires GTP loading for enhanced activity.
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