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A conventional homologous recombination strategy was performed for either targeted gene correction in LQT2-hiPSCsN996I or targeted gene mutation in the NKX2.5 eGFP/w hESCs.
Looking at all of the research, I cannot find a clear political advantage for either targeted or universal social programs (e.g., Greenstein, 1991; Nelson, 2007; Skocpol, 1991).
For either targeted mutations or gene-trapped mutations, transfected mESC clones can be selected after screening for disrupted alleles in the gene of interest.
Furthermore, while this approach is intended to assess the benefit of stable disease, stable disease (unlike response) does not correlate with PFS or survival for either targeted agents or chemotherapy [ 11, 44], and we agree [ 10] with Fojo and Noonan [ 11] that aiming for stable disease is aiming too low.
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We located services specifically for FSWs (either targeted services for sex workers and other at-risk groups, or those integrated within general services) in only 28 of the 58 countries located in Africa.
Internalized membrane proteins can be either targeted for degradation or recycled back to the plasma membrane, as demonstrated in a recent study where COMMD1 down-regulated ENaC trafficking [18].
Ligand binding induces the internalization of the receptor into endosomes, where the receptors are either targeted for ubiquitin-mediated degradation or recycled back to the plasma membrane.
Upon the binding the mRNA, they either target it for degradation or inhibit translation.
However few, if any, have proven effective as a basis for either targeting existing treatments or identifying novel therapeutic approaches in the context of drug resistance.
Here, we should parametrically bootstrap observations for either the target or predictor variable, as doing otherwise would produce data that no longer follows the tree, introducing a bias in the null data.
This ipsilateral performance advantage for either target eccentricity was not reliably affected by whether the hands were aligned with either the inner, or the outer, targets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com