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For each systematic grid, a random forest model was fit with the sampled values and their co-aligned values from the remote sensing layers.
Data analysis involved producing a list of prognostic factors for each systematic review, and then the conclusions obtained from each systematic review were recorded for each factor.
For each systematic sampling grid, the ACD value extracted from the centroid of each sampling grid cell was used as the ACD value for all of the 1-ha values in that sampling grid cell.
Two independent reviewers assessed the RoB for each systematic review.
Detailed eligibility criteria for each systematic review are reported in Additional file 1[ 3- 8].
We recorded the number of included studies that were indexed in MEDLINE for each systematic review.
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We categorised the conclusions of each systematic review for the association of vitamin D and the outcome of interest in one of the following four categories: definite association, suggestive (possible) association, no association, or inconclusive (insufficient) evidence.
We did a known-item search for the included studies of each systematic review that met the three inclusion criteria in OVID MEDLINE (1966 200303) to determine whether they were indexed in MEDLINE or not.
For each animal, systematic pictures were taken with the slide scanner Hamamatsu nanozoomer.
Lastly, we developed user-friendly summaries for each included systematic review.
For each included systematic review, two reviewers independently assessed the methodological quality with the 37 items (CH, BS).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com