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Posterior conditional probabilities of the component membership for each sample were computed using the fitted parameters, and a threshold of ≥0.5 was used to classify a sample as having positive expression of the receptor.
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Chroma samples are computed using four-tap filters.
The distance between two samples is computed using the Pearson Correlation based distance (5).
Confidence intervals for rates were computed using exact binomial methods.
All analyses were computed using SPSS for Windows 14.0.
Statistics were computed using SPSS for Windows 17.0.
AUC values were computed using trapezoidal rule for numerical integration.
P-values were computed using t-tests for the microarray measurements between genotype and DNA methylation for 1000 independent sets of randomly sampled SNPs.
Contrasts were computed using a Bonferroni correction for multiple comparisons.
Trend analyses were computed using joinpoint analysis.
Comparative statistics were computed using SPSS 17.0.
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