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For every reference-floating VOI pair, the floating VOI is transformed according to the scheme outlined in Section 2.4 and for each candidate transformation parameter, the QMI-based similarity measure (6) is calculated.
The similarity measure values were determined for each candidate transformation parameter.
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Each candidate transformation is further evaluated by a scoring function that considers both geometric fit and atomic desolvation energy.
Zero mean Gaussian noise of different variance was added and the values of the similarity measure for different candidate transformation parameters calculated.
The RANSAC-based alignment procedure is straightforward: randomly pick a base ℬ p of N non-collinear points from P ; detect the corresponding best congruent bases { ℬ q k } k = 1 K g and for each one compute the candidate transformation that aligns points in ℬ p with points in ℬ q k ; and finally verify the recovered transformations and detect the best one using a best fit criteria.
Each of the candidate transformation is additionally evaluated by a scoring function which considers both the atomic desolvation energy and geometric fit [ 50].
We used the same primers for each candidate gene and the same transformation strategy as for the two parental strains.
A -level multiresolution approach was adopted where candidate transformation parameters for different DOFs were first calculated at the coarsest level and the solution propagated to finer levels.
Each pair of matched interactions defines a candidate transformation that can superimpose the considered PPI upon the pivot.
Normality of the gene expression data set was rejected by the Shapiro Wilk test and thus a log10 transformation was applied on the dependant variables (gene expression level for each candidate gene).
(a-j) Intermediate results (before the application of morphological transformations) produced by the iterative application of the segmentation step on the patch (and seed) in Figure 2. The characterization phase is aimed at obtaining relevant information for each candidate brushstroke.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com