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This was not accounted for during the randomization process.
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The distribution of the cross-gender differences computed during the randomization procedure for this subcategory for the USA is shown in Figure 3(c).
As an example, Figure 3(a) shows the distribution of the cross-gender differences computed during the randomization procedure for Brazil.
Concern was also raised regarding stratification during the randomization process for sex.
Another reason for this lack of an association is that during the randomization of subjects, more participants with poor metabolic control were placed in the NSPT group.
This method of random reassignment retains the topological network structure of the interactome during the randomization.
These proportions should thus be maintained during the randomization process.
Second, research staff was not blinded for the randomization during the follow up period, although this information was kept in another worksheet in the database than necessary for daily use and information about the randomization was not in their interest.
For example, the randomization procedure was unclear in many studies.
An independent person was responsible for managing the randomization lists.
The first model used ANCOVA including factors for treatment, the randomization covariate of interest, and the randomization stratification variable.
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