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These companies churn out piles of sequenced genomic data, but that data is still too complex for downstream research and clinicians to use.
The determination of the precise sequence of the mature miRNA, including the ends, is essential for downstream research applications in various organisms, such as miRNA target prediction and further studies on miRNA evolution, the regulatory role of miRNAs, and the mechanism of miRNA biogenesis.
This review article, thus, could be a reference point for downstream research in the field of nasopharyngeal carcinoma biomarkers.
Our study makes a large proportion of the functional variation in coding regions of the genome available for downstream research with the use of high throughput genotyping platforms.
While a seemingly benign annotation error, the consequences for downstream research could be detrimental, particularly as the biotic interactions or industrial applications of microbes are largely determined by their secretomes.
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Thus, the sequence provides a solid foundation for a wealth of downstream research activities including marker development, linkage map construction and marker-trait association.
This information, coupled with knowledge of RNA ratios derived from each tissue type, could be useful in gene expression studies, making the sequence information from these libraries valuable for a wide array of downstream research.
This resource forms the foundation for all downstream research in ecology and evolution.
Contrasted to today's broad consent model, a dynamic consent entails narrower, more specific consents with active opt-in requirements for each downstream research project.
Muin J Khoury and colleagues [ 36] found that only 3% of the US National Institutes of Health (NIH) funding was targeted for downstream translational research.
First, since one cannot patent around a gene, as one can for example with a chemical, the patent holder can potentially stymie downstream research on diagnostics and therapeutics.
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