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The gene description, GO annotations were retrieved for each of the DEGs and were used for downstream interpretation of datasets.
As a result, this work illustrates these forms of DNA damage can have major consequences for downstream interpretation as not all actionable mutations could be validated.
With the absence of this information, anchor markers are needed to guide linkage map construction and for downstream interpretation of QTL analysis.
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Furthermore, the collection of FT-MIR, rather than NIR, spectra provides an opportunity for downstream spectral interpretation of cell wall modifications that lead to altered digestibility.
Documentation of potential taxonomic-specific biases in recovery of DNA is critical as they impact downstream interpretations of metagenomic data, affecting accurate description of these ancient microbial ecosystems.
The digital, count-based nature of RNA-Seq provided a number of potential advantages for downstream data analysis and interpretation.
Confero includes a local database for storage and management of data and metadata as well as tools for downstream computational analysis and biological interpretation, including gene set enrichment analysis (GSEA) and over-representation analysis (ORA) [ 17].
For this proteome discovery paper we included single peptide hits and proteins having only 2 peptide identifications for consideration in downstream biological interpretation with the caveat that protein abundance comparisons should be weighted less than the proteins identified with at least 3 peptides [45] [46].
However this interpretation does not explain why a positive relationship is also observed for downstream intergenic sequences [6], if, as a recent study with 61 Arabidopsis thaliana transcription factor genes suggests, the downstream intergenic sequence is generally not required to drive the appropriate gene expression pattern [7].
The predicted binding regions can then be used for downstream analyses, such as motif discovery and annotation, to provide further functional context for the biological interpretation.
Such an approach can provide guidelines for the interpretation and prioritization of predicted somatic variation from matched tumor-germline exome-sequencing data for downstream validation studies (Table 6).
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CEO of Professional Science Editing for Scientists @ prosciediting.com