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Taken together, these data extend upon and support the observations of Hovatta et al [7] which showed a positive relationship between anxiety-like behavior and Glo1 expression, but are inconsistent with studies based on selection for divergent levels of anxiety-like behavior in CD-1 mice, which showed a negative relationship between anxiety-like behavior and Glo1 expression [8], [9], [10], [11].
Many novel loci affecting aggressive behavior have been implicated from widespread correlated responses in gene expression to selection for divergent levels of aggressive behavior [ 26, 27].
In addition, changes in expression levels of Obp genes occur as a correlated response to artificial selection for divergent levels of copulation latency (Mackay et al. 2005) and aggression (Edwards et al. 2006), and expression levels change during social crowding and as a result of ageing (Zhou et al. 2009).
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Thus, divergent levels of adenylate cyclase might represent the basis for the greater cAMP generation in response to PGE2.
Intriguingly, we discovered statistically significant and divergent levels of gene expression between the two isolates profiled for 64 genes.
These refugees are not all living with their immediate needs provided for in the refugee camps, but are spread out in host communities with widely divergent levels of aid.
These proteins show different divergent levels and their functional domains are well characterised and are therefore highly suitable for the purpose of this work.
98% of 1500 kindergartners scored at the genius level for divergent thinking.
Differences in gender, baseline characteristics of subjects and the dietary intervention may account for divergent outcomes in HDL-C levels between men and women.
Therefore, phastCons and AlignMiner appear to be complementary, since phastCons is devoted to conserved fragments while AlignMiner is specialised for divergent regions of MSAs with various levels of similarity.
We note that our ability to find all six RNase PH domain proteins in T. brucei by similarity searches represents an improvement compared to previous studies [ 22, 24] and indicates a high level of sensitivity for divergent protein sequences in our study.
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