Exact(13)
For regional spread at diagnosis, the rate is 78percentt, and for distant spread, 23percentt.
As suggested by ECCO guidelines, search for distant spread is usually performed by means of contrast-enhanced body MDCT, with conventional imaging appearances of liver and lung metastases.
35% for distant spread.
These data underline the importance of stemness-associated markers for the identification of CC with high risk for distant spread.
For Stage II lesions, the corresponding figures are 49% for distant spread compared to 32% for locoregional disease [ 2, 6].
However, in 10-35% of the patients an isolated local recurrence without evidence for distant spread occurs [ 4, 5].
Similar(47)
In summary, our data underline the importance of stemness-associated markers for the prediction of distant spread and the prognostification of CC.
There are evidence-based guidelines for the use of imaging in assessing the presence of distant spread of prostate cancer.
Treatment strategies for localised prostate cancer have to address issues of local control, prevention of distant spread and treatment of microscopic locoregional spread.
According to the literature, the most frequent sites for PTC distant metastases are lungs 72-766% of cases), mediastinum (24%) and bones 19-233%), while there are only sporadic reports of distant spread to other locations.
In patients without further assessment of LC e.g. after development of distant spread, the date of the last information about the local status was used for calculation.
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