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For example, after adjusting for age, gender, smoking, drinking and family history of cancer, a higher risk was observed in the Chinese population 11 while smoking conveyed no increased risk in an Italian population for undifferentiated subtypes of the disease but very high association for differentiated cases with consumption of more than 15 cigarettes/day.
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They would be able to justify the sort of differentiated, case-by-case decisions for which true professionals should be trained.
Thus, expression of MDR1/P-gp is typical for the less differentiated cases of breast cancer.
As for immunohistochemistry, some regions such as poorly differentiated cases can be difficult for even an experienced pathologist to define whether they are cancerous cells or not.
For the 123 cases with tumour grading information available, moderately differentiated cases were the leading finding accounting for 49.6% of cases.
The differentiated case types that emerged from the dual measures of PPR and FTE informed the selection of cases for this study.
The ratio of HNF1α/HNF1β mRNA is higher in well-differentiated cases than in poorly-differentiated and undifferentiated cases.
Thirty-four cases were well differentiated, 89 cases were moderately differentiated, and 27 cases were poorly differentiated.
For analysis purposes, the intermediately differentiated DCIS cases were subclassified as those cases that were in part well differentiated (well to intermediately differentiated) and those that were in part poorly differentiated (moderately to poorly differentiated) in some areas.
Nagahama et al. performed ME-NBI in all cases, reporting a lower successful delineation rate for undifferentiated than for differentiated gastric cancers [ 4].
In our data set of all in situ samples, we found a positive log2-ratio for HER mRNA expression in six of 14 poorly differentiated DCIS cases (43%) and in one case of intermediately-poorly differentiated DCIS.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com