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So what is the biological basis for differential variability?
Availability: The R source code for differential variability analysis is available from the contact authors upon request.
The datasets were tested for differential variability using our F-test-based procedure, and differential expression by Welch's two-sample t-test (Welch, 1947).
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We introduce the concept of differential variability (DV), and present a simple procedure for identifying DV genes from microarray data.
Locating regions of differential variability in DNA and protein sequences.
In fact, our definition of differential variability deliberately includes both increase and decrease of variability between two groups of samples.
In contrast, an analogous classifier that uses differential methylation instead of differential variability statistics could not predict prospective CIN2+ status.
MS and JWKH conceived the idea of differential variability in human ageing.
Here we propose a simple definition of differential variability of a gene between two conditions.
Differential levels of germline expression among species could account for the differential variability of intron-exon structure.
Here we only considered differential variability tests for two-group comparisons because this is the simplest and most common type of experimental data.
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