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To test the robustness of the combined score, weights were inferred from the human-yeast analysis and the same set of values was then used for all subsequent analyses, including human fly, fly yeast and human worm comparisons (In the Supplementary Material, we also determined optimized weights for yeast fly analysis to test how the weights differ for different comparisons).
To estimate the number of clusters, Additional file 1: Figure S9A-D presents the Gap statistics and the incremental differences in each omics data set for different comparisons.
Therefore, based on statistics illustrated in Fig. 11, Table 10 shows the results from a statistical significance test for different comparisons of organisation types by use of the non-parametric Mann-Whitney one-sided u-test16 and the one-sided alternative null hypothesis PROB X > Y) > ½, where X and Y are the samples.
In order to establish tendency of longer (or shorter) development time in standards that have editor participation from a certain country when comparing with a different country, Table 11 shows the results from a statistical significance test (based on statistics illustrated in Fig. 12), for different comparisons of countries by use of the Mann-Whitney test.
We visualized this change, using deformation grids for different comparisons (figure 4).
The significantly differentially expressed gene lists for different comparisons were generated and outputted as Excel sheets.
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A binomial distribution B i (m, p aa ) was modeled for each amino acid species at each position, where p aa was set as p(A i ) of negative dataset or 1/20 (ideal random situation) for different comparison purpose.
These effects were differently lateralized for the different comparisons.
Finally, simulated datasets are designed for the different comparisons and the model is illustrated using the real data.
Rankings were made for three different comparisons; relapse versus remitting, remitting versus controls and relapse versus controls.
N was 140 or 141 for the different comparisons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com