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This study was designed with the objectives of better defining the impact of infection, examining the occurrence of extraintestinal manifestations, and determining risk factors for delayed treatment of infection.
Several factors act as limitations on the analysis of reasons for delayed treatment.
[35], [36], [37] Moreover, early ARV initiation has been associated with decreased mortality [38], [39], and our data also show that food insecurity is a risk factor for delayed treatment initiation.
The 1-year survival was 57% for immediate treatment and 46% for delayed treatment.
We found that the main reason for delayed treatment initiation was patients' limited access to finance.
For delayed treatment, a patient was assigned a time from diagnosis to vision falling below 6/12.
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The case for delaying treatment has gained strength as optimism has faded that the new therapies are a cure, and as people have become more concerned about dangerous side effects and the appearance of drug-resistant H.I.V. strains.
Our study did not directly explore fear of side effects as a potential reason for delaying treatment.
The desire to reserve medication for a severe migraine was the most common reason given for delaying treatment, reported in fully half the patients who wanted to treat earlier.
Various reasons for delaying treatment are summarized in Table 1.
The frightening supernatural force was most often responsible for delaying treatment in Matlab (rural setting).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com