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More patients with two catheters would be needed for definitive evaluation.
Larger studies are needed for definitive evaluation of the effect of aspirin in patients treated with insulin.
Delay of elective scheduled surgery for definitive evaluation of newly detected anaemia and associated clinical conditions (nutritional deficiency, chronic renal disease, etc).
Clinical and pathologic correlations were recommended, as well as a repeat PET/CT of the vertex through the feet, for definitive evaluation of the dermis.
Although large longitudinal studies like the ongoing ADNI trial will be required for definitive evaluation, present data suggest that PET amyloid imaging has the potential to promote earlier and more specific diagnosis of dementia.
The entire feasibility study, together with our previous work relating to the original NLNY intervention 8 and the related qualitative studies, including the interview study reported here, 9 will inform plans for optimisation of the intervention and options for definitive evaluation of the NLNY intervention for effectiveness and cost-effectiveness.
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Aiming for a definitive evaluation of Hamilton, Mr. Chernow delivers a comprehensiveness that rivals Hamilton's The latter half of "Alexander Hamilton" is the more vivid, perhaps because the man was left adrift and reckless after a meteoric early career.
First, the sample sizes are too small for a definitive evaluation of the complex issue we seek to investigate.
This feasibility assessment will also inform future options for a definitive evaluation of the adapted NLNY programme.
18 Finally, studies should be conducted not necessarily to be definitive, but rather to prepare for a definitive evaluation study (preferably a randomised controlled trial).
There are now sufficient epidemiologic studies in place that will provide a better climate for a definitive evaluation in the near future.
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