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While older generations have often preferred to rely on traditional workers for core positions, this generation may have different attitudes about that.
On the other, the consolidation of existing value chains raises the stakes in terms of the competition for core positions.
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So it will be necessary to "compensate for our core positions and perhaps one day to have a full-time staff".
This continuous check for the core positions and regular positions leads to very effective pruning.
Whereas for matches at DUES core positions, Nucexp was calculated using equation 11 for Ws, and 12 for Ss.
Potential amino acids that correlate with the propensity data for each core position of all the screened folds are then identified for the target sequences, providing an estimate of 'core fit' and serving as a second filter for fold and template selection.
For mismatches at DUES core positions, however, calculation of Nucexp depends on the nature of both the mismatched nucleotide in question and the DUES match at the same position.
(c) gives the core thresholds for each prefix over core positions in each component.
The negative selection was stronger for transcriptional repressors as compared with transcriptional activators or multifunctional TFs as well as for core TFBS positions as compared with flanking TFBS positions.
In fact, before applying scores over all positions, we first consider the scores for the prefixes of the core positions within the component.
Table 3 gives the (exponentiated) entropy, averaged over the entire polypeptide chain, or over the core positions only (except for the SKIs, where the protein core is very small).
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